Mild hypothermia reduces cardiac post-ischemic reactive hyperemia
نویسندگان
چکیده
منابع مشابه
Mild hypothermia reduces cardiac post-ischemic reactive hyperemia
BACKGROUND In experimentally induced myocardial infarction, mild hypothermia (33-35 degrees C) is beneficial if applied prior to ischemia or reperfusion. Hypothermia, when applied after reperfusion seems to confer little or no benefit. The mechanism by which hypothermia exerts its cell-protective effect during cardiac ischemia remains unclear. It has been hypothesized that hypothermia reduces t...
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BACKGROUND Mitochondrial dysfunction is critical following ischemic disorders. Our goal was to determine whether mild hypothermia could limit this dysfunction through per-ischemic inhibition of reactive oxygen species (ROS) generation. METHODS First, ROS production was evaluated during simulated ischemia in an vitro model of isolated rat cardiomyocytes at hypothermic (32°C) vs. normothermic (...
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Objective(s):To investigate the effects of local mild hypothermia on the expression of Fas, FasL and MMP-3 after cerebral ischemia-reperfusion in rats. Materials and Methods:Male Wistar rats were divided into sham-operated group (Sham), normothermia group (NT), and hypothermia group (HT). MCAO/R model was established by Longa’s method, and reperfusion was allowed after 2 hr occlusion. Mild hypo...
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. Nappo F, Esposito K, Cioffi M, et al. Postprandial endothelial tion in healthy subjects and in type 2 diabetic patients: role of carbohydrate meals. J Am Coll Cardiol 2002;39:1145–50. . Ferreira AC, Peter AA, Mendez AJ, et al. Postprandial hypertrig idemia increases circulating levels of endothelial cell micropart Circulation 2004;110:3599 – 603. . Esposito K, Nappo F, Giugliano F, et al. Eff...
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ژورنال
عنوان ژورنال: BMC Cardiovascular Disorders
سال: 2007
ISSN: 1471-2261
DOI: 10.1186/1471-2261-7-5